Zadig driver windows 10

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What I want to do is use one of the adapters with the 'standard' FTDI VCP Driver and the second adapter via libusk and python (libftdi). One of the adapters has an FT245R inside, the other one an FT232R (I see that by reading the device information with the FT_Prog tool from FTDI).

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I use two kinds of USB/Serial Adapters on the same PC (Windows 8 / Windows 10). I have found related questions on this topic, but not an answer to this specific question (at least none that is a solution).